Antiviral therapy of influenza

作者：McCullers JA^*

来源：Expert Opinion on Investigational Drugs, 2005, 14(3): 305-312.

DOI：10.1517/13543784

• amantadine
• antiviral
• influenza
• oseltamivir
• pandemic
• rimantadine
• zanamivir

Influenza viruses are a leading cause of morbidity and mortality worldwide despite the availability of an effective vaccine. The emergence of highly pathogenic avian influenza viruses in southeast Asia, which can infect and kill humans and for which there is no vaccine, has heightened the need to establish a supply of effective antivirals. Two effective classes of anti-influenza drugs are currently available, and many attractive targets exist for further development. This review presents the current status of antiviral therapy of, and highlights the challenges presented by, the threat of pandemic influenza.

• 出版日期2005-3