A Facile One-Pot Synthesis of Functionalized 4,8-Dihydropyrano[3,2-b]-pyran-4-ones

作者：Asghari Sakineh^*; Ahmadipour Mohammad

来源：Acta Chimica Slovenica, 2010, 57(4): 953-956.

• Kojic acid
• dialkyl acetylenedicarboxylate
• tert-butyl isocyanide
• cyclohexyl isocyanide
• 4,8-dihydropyrano[3,2-b]pyran-4-one

The reactive intermediates generated by the addition of alkyl isocyanides and dialkyl acetylenedicarboxylates were trapped by 5-hydroxy-2-hydroxymethyl-4H-pyran-4-one (kojic acid) to yield functionalized 4,8-dihydropyrano[3,2-b]-pyran-4-ones at ambient temperature in good yields.

• 出版日期2010