Application of ionic liquid-TiO2 nanoparticle modified carbon paste electrode for the voltammetric determination of benserazide in biological samples

作者：Ensafi Ali A^*; Bahrami Hajar; Rezaei B; Karimi Maleh Hassan

来源：Materials Science & Engineering C-Materials for Biological Applications, 2013, 33(2): 831-835.

DOI：10.1016/j.msec.2012.11.008

• Benserazide analysis
• Ionic liquid
• TiO2 nanoparticles
• Carbon paste electrode
• Voltammetry

An ionic liquid-TiO2 nanoparticle modified carbon paste electrode (IL-TiO2/CPE) was used as a fast and sensitive tool for the investigation of the electrochemical oxidation of benserazide using voltammetry. This modified electrode has been fabricated using hydrophilic ionic liquid (n-hexyl-3-methylimidazolium hexafluoro phosphate) as a binder. The modified electrode offers a considerable improvement in voltammetric sensitivity toward benserazide, compared to the bare electrode. Using differential pulse voltammetry (DPV), the electrocatalytic oxidation peak current of benserazide shows a linear calibration curve in the range of 1.0-600 mu mol L-1 benserazide. The limit of detection was equal to 0.4 mu mol L-1. The relative standard deviation (RSD%) for eight successive assays of 10 mu mol L-1 benserazide was 1.1%. Finally, the proposed method was successfully applied to the determination of benserazide in real samples such as blood serum and urine.

• 出版日期2013-3-1