Divergence of affinities, serotypes and virulence factor between CTX-M Escherichia coli and non-CTX-M producers

作者：Ding, Hai-feng; Liu, Bao-guang; Gao, Yan-ling; Zhong, Xing-hao; Duan, Sha-sha; Yuan, Li^*

来源：POULTRY SCIENCE, 2018, 97(3): 980-985.

DOI：10.3382/ps/pex376

• serogroups
• virulence factors
• multi-locus sequence typing
• CTX-M-1cluster
• CTX-M-9 cluster

This study was undertaken to discern the differences of the multi-locus sequence typing (MLST), O serogroups, and virulence factors among 34 CTX-M-1 Escherichia coli, 49 CTX-M-9 strains and 23 non-CTX-M isolates from chickens in Henan province, China. The MLST scheme yielded 34 sequence types, in which ST155 and ST359 were frequent (17% and 15%, respectively) and associated with zoonotic disease. The irp-2 (20% versus 2%, P = 0.0001), traT (85.3% versus 56.5%, P = 0.019), and sfaS (70.6% versus 0, P = 0.021) were significantly more prevalent in CTX-M-1 E. coli than in non-CTX-M producers. Also, CTX-M-9 isolates carried more irp-2 (17% versus 2%, P = 0.023), iroN (71.4% versus 39.1%, P = 0.019), and iss (79.6% versus 39.1%, P = 0.002) genes. In conclusion, although the 106 isolates encompassed a great genetic diversity, the CTX-M isolates harbored more virulence factor genes than non-CTX-M producers.

• 出版日期2018-3
• 单位河南农业大学