Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue

作者：Docimo Giovanni^*; Limongelli Paolo; Conzo Giovanni; Gili Simona; Bosco Alfonso; Rizzuto Antonia; Amoroso Vincenzo; Marsico Salvatore; Leone Nicola; Esposito Antonio; Vitiello Chiara; Fei Landino; Parmeggiani Domenico; Docimo Ludovico

来源：BMC Surgery, 2013, 13(Suppl 2): S8.

DOI：10.1186/1471-2482-13-S2-S8

Background: Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results. %26lt;br%26gt;Methods: Thirty patients over 60 years underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray were applied to the axillary fossa in 15 patients; the other 15 patients were treated with harmonic scalpel. %26lt;br%26gt;Results: Suction drainage was removed between post-operative Days 3 and 4. Seroma magnitude and duration were not significant in patients receiving fibrin glue compared with the harmonic scalpel group. %26lt;br%26gt;Conclusions: Use of fibrin glue does not always prevent seroma formation, but can reduce seroma magnitude, duration and necessary evacuative punctures.

• 出版日期2013-10-8