Using a bacterial fucose-rich polysaccharide as encapsulation material of bioactive compounds

作者：Lourenco Sofia C; Torres Cristiana A V; Nunes Daniela; Duarte Paulo; Freitas Filomena; Reis Maria A M; Fortunato Elvira; Moldao Martins Margarida; da Costa Luisa Beirao; Alves Vitor D^*

来源：International Journal of Biological Macromolecules, 2017, 104: 1099-1106.

DOI：10.1016/j.ijbiomac.2017.07.023

• FucoPol
• Spray drying
• Microencapsulation
• Gallic acid
• Oregano essential oil

The potential of a bacterial exopolysaccharide named FucoPol, produced by the bacterium Enterobacter A47, as encapsulation matrix was explored. Spherical capsules with a smooth surface were produced by spray drying. The obtained microcapsules had average diameters ranging from 0.5 to 26.7 m and presented thin walls (thickness from 222 to 1094 nm). The capsules were loaded with two bioactive compounds: gallic acid (GA) and oregano essential oil (OEO). Both bioactive materials were encapsulated in FucoPol particles, retaining their antioxidant activity after the drying process. Release studies showed that GA release in simulated gastric and intestinal fluids was faster than that of OEO, envisaging that the latter had established stronger interactions with the polymer matrix. These results suggest that FucoPol has a good potential for use as encapsulating material of bioactive compounds for application in several areas, including food, cosmetic or pharmaceutical products.

• 出版日期2017-11