Ultrasound-promoted synthesis of 3-[(acetamido)(aryl)methyl]-4-hydroxy-6-methyl-2H-pyran-2-ones via a three-component condensation

作者：Bizhanpoor Nafiseh; Hassanabadi Alireza^*

来源：Journal of Chemical Research, 2016, 40(1): 38-39.

DOI：10.3184/174751916X14495896655773

• ultrasound
• 4-hydroxy-6-methyl-2H-pyran-2-one
• p-toluenesulfonic acid
• three-component reaction
• aryl aldehydes
• acetamide

A three-component one-pot condensation of aryl aldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one and acetamide catalysed by p-toluenesulfonic acid (p-TSA), under ultrasound irradiation and ambient conditions, gives 3-[(acetamido)(aryl)methyl]-4-hydroxy-6-methyl-2H-pyran-2-ones in excellent yield and in short time.

• 出版日期2016-1