Mass spectrometry in microbiology: A revolution

作者:Martiny D*; Vandenberg O
来源:Immuno-Analyse & Biologie Specialisee, 2012, 27(4): 177-184.
DOI:10.1016/j.immbio.2012.04.005

摘要

Since a few years, mass spectrometry constitutes a new promising tool in microbiology. Allowing a fast and reliable identification of microorganisms, Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) competes with traditional identification techniques. More recently, direct identification of bacteria and yeasts directly from clinical samples was described. Next to identification and typing applications, MALDI-TOF MS and other recent mass spectrometric technologies such as SELDI-TOF MS and PCR-ESI-MS are interesting tools for genotyping and testing bacterial susceptibility.

  • 出版日期2012-8