A pH Responsive Redox Hydrogel for Electrochemical Detection of Redox Silent Biocatalytic Processes. Control of Hydrogel Solvation

作者：Contin Andrea; Frasca Stefano; Vivekananthan Jeevanthi; Leimkuehler Silke; Wollenberger Ulla; Plumere Nicolas^*; Schuhmann Wolfgang

来源：Electroanalysis, 2015, 27(4): 938-944.

DOI：10.1002/elan.201400621

• pH responsive hydrogel
• External stimuli
• Biofuel cell
• Self-powered biosensor
• Solvation

The control of bioelectrocatalytic processes by external stimuli for the indirect detection of non-redox active species was achieved using an esterase and a redox enzyme both integrated within a redox hydrogel. The poly( vinyl) imidazole Os(bpy)(2)Cl hydrogel displays pH-responsive properties. The esterase catalysed reaction leads to a local pH decrease causing protonation of imidazole moieties thus increasing hydrogel solvation and mobility of the tethered Os-complexes. This is the key step to enable improved electron transfer between an aldehyde oxidoreductase and the polymer-bound Os-complexes. The off-on switch is further integrated in a biofuel cell system for self-powered signal generation.

• 出版日期2015-4