Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati

作者：Du, Fu You; Mao, Xiao Hua; Li, Gong Ke^*

来源：Journal of Chromatography A, 2007, 1140(1-2): 56-62.

DOI：10.1016/j.chroma.2006.11.049

• ionic liquids
• MAE
• trans-resveratrol
• Rhizma Polygoni Cuspidati
• HPLC

In this paper, the application of 1-n-butyl -3-methylimidazolium-based ionic liquids aqueous solutions as solvents in the microwave-assisted extraction (MAE) technique was first developed for the extraction of trans-resveratrol from Rhizma Polygoni Cuspidati. 1-butyl-3-methylimidazolium bromide ([bmim]Br) solution was selected as solvent; the conditions of MAE including the size of sample, liquid/solid ratio, extraction temperature and time were optimized by means of an orthogonal design L-9(3(4)). Under optimized conditions, the extraction yield value of trans-resveratrol was 92.8% in a one-step extraction. The recovery was in the range 93.7-103.2% with relative standard deviation lower than 3.0% by the proposed procedure. The method was applied to extract trans-resveratrol from several different region samples. On the basis of extraction solvent and time, the proposed extraction technique was a green, rapid and alternative technique to extract and analyze trans-resveratrol in Rhizma Polygoni Cuspidati samples.

• 出版日期2007-1-26
• 单位中山大学