Analysis of Numerous Androgen Disruptors in Fish by Gas Chromatography Tandem Mass Spectrometry

作者：Liu, Shaoying; Bian, Tianbin; He, Huali; Huang, Xihui; Jin, Quan; Wang, Shuting^*; Zhu, Guonian

来源：Journal of AOAC International, 2017, 100(3): 647-652.

DOI：10.5740/jaoacint.16-0283

• ORGANOCHLORINE PESTICIDE-RESIDUES
• ENDOCRINE DISRUPTORS
• HEALTH
• RIVER
• VINCLOZOLIN
• EXPOSURE
• BASIN
• WATER

An improved analytical method was developed for the simultaneous quantification of numerous androgen disruptors vinclozolin, dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes, chlordane, heptachlor, dieldrin, endrin, and aldrin-in fish, followed by GC with tandem MS (MS/MS). Extraction, cleanup, and MS/MS parameters of analytes were optimized. The LOQs of the analytes ranged from 0.3 to 3.7 mu g/kg. Reasonable recoveries (73.7-119.2%) were demonstrated at different spike levels with RSDs lower than 12.2%. This method was applied for the analysis of the target analytes in fish samples sold in Hangzhou, China, and DDTs were found to be the predominant contaminants in fish samples.

• 出版日期2017-5
• 单位浙江大学; 杭州市疾病预防控制中心