AN EFFICIENT SYNTHESIS OF 1,2,3-TRIAZOLE BRIDGE-CONNECTED PHOSPHONATE DERIVATIVES OF COUMARIN

作者:Li, Xu; Chen, Xiaolan*; Yuan, Jinwei; Liu, Yang; Li, Peipei; Qu, Lingbo; Zhao, Yufen
来源:Phosphorus, Sulfur, and Silicon and the Related Elements, 2015, 190(7): 961-971.
DOI:10.1080/10426507.2014.979987

摘要

An efficient general synthetic approach giving the possibility of a facile access to a wide range of novel 1,2,3-triazole bridge-connected phosphonate derivatives of coumarin, based on a copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition, has been developed. Under the optimized conditions, a novel series of 1,2,3-triazole bridge-connected phosphonate derivatives of coumarin was synthesized in high yields, and their structures were elucidated by NMR, IR, and HR MS.