Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation

作者：Honda Akiko; Watanabe Chiho; Yoshida Minoru; Nagase Hisamitsu; Satoh Masahiko^*

来源：Journal of Toxicological Sciences, 2013, 38(1): 151-153.

DOI：10.2131/jts.38.151

• Cadmium
• Microarray
• Neonatal brain
• Transferrin receptor (Tfrc)

DNA microarray containing 30,000 genes was used to monitor the transcriptional response of the neonatal brain after cadmium (Cd) exposure. C57BL/6J pregnant mice were exposed to Cd (10 ppm) during gestation and lactation via drinking water. In a comparison between the Cd-exposed neonatal brain and control, three genes including transferrin receptor (Tfrc) were up-regulated and one gene was down-regulated.

• 出版日期2013-2