Are Hemoglobin Levels Elevated in Type 1 Diabetes?

作者：Conway Baqiyyah N; Miller Rachel G; Orchard Trevor J^*

来源：Diabetes Care, 2010, 33(2): 341-343.

DOI：10.2337/dc09-0713

OBJECTIVE - While lower hemoglobin is generally associated with adverse events in diabetes, we have recently observed in type I diabetes that those with overt nephropathy had hemoglobin levels as high as 1.8.8 g/dl. We thus explored whether hemoglobin concentrations are generally higher in type I diabetes.
RESEARCH DESIGN AND METHODS - Baseline (1986-1988) hemoglobin levels from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) of type I diabetes were compared, with general population data from the National Health and Nutrition Examination Survey (NHANES) III in the same age range as the EDC population (aged 8-48 years).
RESULTS - Both male and female EDC Study participants had significantly higher hemoglobin levels than their NHANES III counterparts (men: 16.0 vs. 15.1 g/dl, P < 0.0001; women: 1.4.1 vs. 13.3 g/dl, P < 0,0001). The difference between the two populations was greatest in adolescent female subjects.
CONCLUSIONS - Hemoglobin levels may be higher in type I diabetes than in the general population, which may have important clinical implications.

• 出版日期2010-2