Determination of the enantiomeric purity and the in-process control by HPLC in the technology for production of optically active ingredients on an example of tolterodine tartrate

作者：Puchalska Maria^*; Zagrodzka Joanna; Czerniec Michalik Ewelina; Zezula Maria; Chmiel Justyna; Luniewski Wojciech; Zagrodzki Bogdan

来源：Przemysl Chemiczny, 2012, 91(3): 358-364.

Applicability of the isocratic chiral high-performance liq. chromatog. with UV detection for detn. of the enantiomeric purity of active pharmaceutical ingredients was successfully tested on an example of (R)-2-[3-(diisopropylamino)1-phenylpropyl]-4-methylphenyl L-(+)-tartarate. Contents of both (R) and (S) isomers were detd.

• 出版日期2012-3