Burden of Malaria during Pregnancy at the Time of IPTp/SP Implementation in Gabon

作者：Bouyou Akotet Marielle K^*; Nzenze Afene Solange; Ngoungou Edgard B; Kendjo Eric; Owono Medang Mathieu; Lekana Douki Jean Bernard; Obono Obiang Ghislaine; Mounanga Mathieu; Kombila Maryvonne

来源：The American Journal of Tropical Medicine and Hygiene, 2010, 82(2): 202-209.

DOI：10.4269/ajtmh.2010.09-0267

The new recommendations to prevent malaria in pregnant women have recently been implemented in Gabon. There is little information on the pregnancy indicators that are Useful for their evaluation. A cross-sectional study for the assessment of the prevalence of peripheral, placental, and cord malaria and anemia among delivering women was performed at the largest public hospital of Gabon. Malaria prevalence was 34.4%, 53.6% and 18.2% for maternal peripheral, placental, and cord blood respectively, with no difference between primigravidae and multigravidae. Submicroscopic infections were frequent and concerned all the positive cord samples. Maternal peripheral, late placental, and cord infections were all associated with a reduced mean birth weight in primigravidae (P = 0.02). Anemia prevalence was 53%, low birth rate was 13%, and prematurity was 25%. The use of intermittent preventive treatment With sulfadoxine-pyrimethamine (greater than or equal to one dose) combined with bed net was associated with a reduction in infection only in multigravidae and with a reduced risk of maternal anemia.

• 出版日期2010-2