Adjustable, rapidly switching microfluidic gradient generation using focused travelling surface acoustic waves

作者：Destgeer Ghulam; Im Sunghyuk; Ha Byung Hang; Jung Jin Ho; Ansari Mubashshir Ahmad; Sung Hyung Jin^*

来源：Applied Physics Letters, 2014, 104(2): 023506.

DOI：10.1063/1.4862322

We demonstrate a simple device to generate chemical concentration gradients in a microfluidic channel using focused travelling surface acoustic waves (F-TSAW). A pair of curved interdigitated metal electrodes deposited on the surface of a piezoelectric (LiNbO3) substrate disseminate high frequency sound waves when actuated by an alternating current source. The F-TSAW produces chaotic acoustic streaming flow upon its interaction with the fluid inside a microfluidic channel, which mixes confluent streams of chemicals in a controlled fashion for an adjustable and rapidly switching gradient generation.

• 出版日期2014-1-13