Does living in crowded houses offer protection against the development of inflammatory bowel disease?

作者：El Tawil A M^*; Nightingale P; Cox M A

来源：European Review for Medical and Pharmacological Sciences, 2013, 17(5): 632-635.

• Crohn's disease
• ulcerative colitis
• IBD
• Hygiene hypothesis
• Helminths
• Asians

INTRODUCTION: The credibility of the "Hygiene hypothesis" in patients with inflammatory bowel disease has been assessed.
OBJECTIVE: This survey is aimed at finding an answer for the question: "Does living in crowded or overcrowded houses protect against the development of inflammatory bowel disease?"
PATIENTS AND METHODS: Asian immigrants to the United Kingdom who attended inflammatory bowel diseases' clinics during the period of the study and who fulfilled Leonard-Jones criteria were asked to complete a questionnaire. The participants were asked to respond to questions on age, sex, their birth rank, diagnosis, & number of brothers, sisters, sons and daughters
RESULTS: 60% of the participants had four or more brothers and sisters. Forty per cent of the participants grew in crowded houses (occupied the fourth birth rank).
CONCLUSIONS: Our presented data do not support any role of the number of house inhabitants in the development of inflammatory bowel disease.

• 出版日期2013-3