Direct Synthesis of N-H Carbazoles via Iridium(III)-Catalyzed Intramolecular C-H Amination

作者：Suzuki Chiharu; Hirano Koji; Satoh Tetsuya^*; Miura Masahiro

来源：Organic Letters, 2015, 17(6): 1597-1600.

DOI：10.1021/acs.orglett.5b00502

The iridium-catalyzed dehydrogenative cyclization of 2-aminobiphenyls proceeds smoothly in the presence of a copper cocatalyst under air as a terminal oxidant through intramolecular direct C-H amination to produce N-H carbazoles. A similar iridium/copper system can also catalyze the unprecedented dimerization reaction of 2-aminobiphenyl involving 2-fold C-H/N-H couplings.

• 出版日期2015-3-20