Nucleophilic Addition of 4-Hydroxycoumarin to Baylis-Hillman Acetate Adducts

作者：Reddy Chada Raji^*; Kiranmai Nayani; Johny Kancharla; Pendke Mrunal; Naresh Police

来源：Synthesis, 2009, 2009(3): 399-402.

DOI：10.1055/s-0028-1083313

• Baylis-Hillman adduct
• hydroxycoumarin
• nucleophilic addition
• 3-substituted coumarin
• potassium carbonate

The exploration of 4-hydroxycoumarin for nucleophilic addition on to Baylis-Hillman acetate adducts has been described for the first time. The reactions of various Baylis-Hillman acetate adducts were examined with 4-hydroxycoumarins in the presence of base to produce the corresponding 3-substituted 4-hydroxycoumarins in good yields.

• 出版日期2009-2-2