DRAW plus SneakPeek: Analysis workflow and quality metric management for DNA-seq experiments

作者：Lin Chiao Feng; Valladares Otto; Childress D Micah; Klevak Egor; Geller Evan T; Hwang Yih Chii; Tsai Ellen A; Schellenberg Gerard D^*; Wang Li San

来源：Bioinformatics, 2013, 29(19): 2498-2500.

DOI：10.1093/bioinformatics/btt422

We report our new DRAW_SneakPeek software for DNA-seq analysis. DNA resequencing analysis workflow (DRAW) automates the workflow of processing raw sequence reads including quality control, read alignment and variant calling on high-performance computing facilities such as Amazon elastic compute cloud. SneakPeek provides an effective interface for reviewing dozens of quality metrics reported by DRAW, so users can assess the quality of data and diagnose problems in their sequencing procedures. Both DRAW and SneakPeek are freely available under the MIT license, and are available as Amazon machine images to be used directly on Amazon cloud with minimal installation.

• 出版日期2013-10-1