Asymmetric transfer hydrogenation of quinolines using tethered Ru(II) catalysts

作者：Parekh Vimal; Ramsden James A; Wills Martin^*

来源：Tetrahedron: Asymmetry , 2010, 21(11-12): 1549-1556.

DOI：10.1016/j.tetasy.2010.03.053

The first report of an asymmetric transfer hydrogenation, in formic acid/triethylamine, of quinolines is described. Using a Ru(II) catalyst containing a 4-carbon tether, products of up to 73% ee were formed, whilst a Rh(III)-tethered catalyst gave products of up to 94% ee.

• 出版日期2010-6-23