Drug and alcohol trajectories among adults with schizophrenia: Data from the CATIE study

作者：Van Dorn Richard A^*; Desmarais Sarah L; Tueller Stephen J; Jolley Jennifer M; Johnson Kiersten L; Swartz Marvin S

来源：Schizophrenia Research, 2013, 148(1-3): 126-129.

DOI：10.1016/j.schres.2013.05.006

• Drug use
• Alcohol use
• Schizophrenia
• Longitudinal
• Growth mixture model

Objective: The primary aim is to describe drug and alcohol trajectories in adults with schizophrenia. %26lt;br%26gt;Method: Growth mixture models were used to examine disordered and non-disordered use and abstinence in the Clinical Antipsychotic Trials of Intervention Effectiveness study. %26lt;br%26gt;Results: Five classes - always abstinent; fluctuating use, abuse, and occasional abstinence; occasional (ab) use; stopped (ab) use; abusing - fit best. Overlap exists between always abstinent drug and alcohol classes; less overlap exists across other classes. %26lt;br%26gt;Conclusion: There is heterogeneity in drug and alcohol use among adults with schizophrenia. The lack of overlap between classes, save always abstinent, suggests modeling drug and alcohol use separately.

• 出版日期2013-8