A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes

作者：Chamorro Cristina; Kruijtzer John A W; Farsaraki Marina; Balzarini Jan; Liskamp Rob M J^*

来源：Chemical Communications, 2009, (7): 821-823.

DOI：10.1039/b817357e

In this Communication, the access to three different peptide loops attached to a small triazacyclophane (TAC) scaffold molecule for the mimicry of discontinuous epitopes present in, for example, antibodies is described for the first time.

• 出版日期2009
• 单位河北医科大学