Analysis of cohesion forces between monodisperse microparticles with rough surfaces

作者：Baldelli Alberto; Vehring Reinhard

来源：Colloids and Surfaces A: Physicochemical and Engineering Aspects , 2016, 506: 179-189.

DOI：10.1016/j.colsurfa.2016.06.009

• Particle engineering
• Drug delivery
• Cohesion forces
• Crystal size
• Atomic force microscope
• Monodisperse and monomorph microparticles

This project investigated the impact of roughness, morphology and crystal size on the cohesion forces between microparticles of different size and shape. A chain of droplets with an initial diameter of about 70 mu m was used for the production of monodisperse and monomorph microparticles in a diameter range of 0.7-17 mu m Droplets were composed of sodium nitrate and deionized water. Initial conditions of the process differed in temperature of the external environment, from 50 to 150 degrees C, and in solution concentration, from 5 to 5.10(-4) mg/mL. By varying these initial conditions, microparticles with different diameter and morphology were generated. Their root mean squared roughness was in a range from 2 to 6.10(-5) mu m. Pull-off forces between particles of the same morphology and of different morphology were determined using colloidal probe microscopy. A wide range of cohesion forces was measured and was found to be affected primarily by the microparticle roughness. The utility of several theoretical cohesion models in predicting the experimental results was tested.

• 出版日期2016-10-5