Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea

作者：Kim Sue Jung; Kim Heejung; Seo Younghee; Yong Dongeun; Jeong Seok Hoon; Chong Yunsop; Lee Kyungwon^*

来源：Diagnostic Microbiology and Infectious Disease, 2010, 67(2): 198-201.

DOI：10.1016/j.diagmicrobio.2010.01.007

• Clostridium difficile
• Toxin A-negative
• toxin B-positive (A(-)B(+))
• Pulsed-field gel electrophoresis (PFGE)

A(-)B(+) Clostridium difficile strains are prevalent in Korea. We performed pulsed-field gel electrophoresis (PFGE), polymerase chain reaction ribotyping, and toxinotyping in 82 A(-)B(+) clinical isolates in Korea. PFGE showed highest discriminatory capability among the 3 methods. By PFGE, persistence of a clone was found, suggesting this clone has adapted to the hospital environment.

• 出版日期2010-6