Maintaining Muscle Mitochondria via Transsynaptic Signaling

作者：Long Jennifer B; Van Vactor David^*

来源：Developmental Cell, 2012, 22(2): 238-239.

Dominant VAPB mutations are implicated in neurodegenerative disease, including amyotrophic lateral sclerosis and spinal muscular atrophy. In the current issue, Han et al. (2012) uncover a mechanism through which the secreted VAPB MSP domain regulates actin organization and mitochondrial function in muscle cells through LAR and Robo receptor activation.

• 出版日期2012-2-14