A Novel Cell Death Gene Acts to Repair Patterning Defects in Drosophila melanogaster

作者:Tanaka Kentaro M*; Takahashi Aya; Fuse Naoyuki; Takano Shimizu Kouno Toshiyuki
来源:Genetics, 2014, 197(2): 739-U502.
DOI:10.1534/genetics.114.163337

摘要

Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.

  • 出版日期2014-6