科研之友
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摘要
A chromium-mediated novel synthesis of carbohydrate-derived di- and trisubstituted (E)-alpha,beta-unsaturated esters or amides from a range of dichloroesters or amides and a variety of sugar aldehydes is reported. The process took place with total stereoselectivity and in high yields. A mechanism based on a sequential chromium-promoted aldol-type reaction and a completely stereoselective beta-elimination reaction is proposed to explain these results.
- 出版日期2011-7-1
