A novel reverse genetics system for human norovirus

作者：Taube Stefan; Wobus Christiane E^*

来源：Trends in Microbiology, 2014, 22(11): 604-606.

DOI：10.1016/j.tim.2014.10.001

• norovirus reverse genetics system
• generation of reporter-tagged viruses

Human noroviruses cause significant morbidity, mortality, and economic losses worldwide. The inability to grow human noroviruses in cell culture has hampered our collective understanding of virus host interactions and development of therapeutics. A newly described single-plasmid reverse genetics system for noroviruses has the potential to facilitate basic and applied research.

• 出版日期2014-11