Use of residual dipolar couplings in conformational analysis of meta-disubstituted calix[4]arenes

作者:Vrzal Lukas; Flidrova Karolina; Tobrman Tomas; Dvorakova Hana; Lhotak Pavel*
来源:Chemical Communications, 2014, 50(57): 7590-7592.
DOI:10.1039/c4cc02274b

摘要

Dimercuration of tetrapropoxy calix[4]arene followed by a reaction with isoamyl nitrite afforded dinitroso regioisomers with unique substitution patterns. The unusual conformational behaviour of these inherently chiral systems was revealed by the combination of dynamic NMR and residual dipolar coupling (RDC) techniques.

  • 出版日期2014