A cholesterol biosensor based on gold nanoparticles decorated functionalized graphene nanoplatelets

作者：Aravind Sasidharan Sasikala Jyothirmayee; Baby Aravind Tessy Theres; Arockiadoss Thevasahayam; Rakhi Raghavan Baby; Ramaprabhu Sundara^*

来源：Thin Solid Films, 2011, 519(16): 5667-5672.

DOI：10.1016/j.tsf.2011.03.032

• Graphene nanoplatelets
• Nafion
• Gold nanoparticles
• Biosensor

The fabrication of a cholesterol biosensor using gold nanoparticles decorated graphene nanoplatelets has been reported. Thermally exfoliated graphene nanoplatelets act as a suitable support for the deposition of Au nanoparticles. Cholesterol biosensor electrodes have been constructed with nafion solubilized functionalized graphene nanoplatelets (f-G) as well as Au nanoparticles decorated f-G, immobilized over glassy carbon electrode. f-G and Au/f-G thin film deposited glassy carbon electrodes were further functionalized with cholesterol oxidase by physical adsorption. Au nanoparticles dispersed over f-G demonstrate the ability to substantially raise the response current. The fabricated electrodes have been tested for their electrochemical performance at a potential of 0.2 V. The fabricated Au/f-G based cholesterol biosensor exhibits sensitivity of 314 nA/mu M cm(2) for the detection of cholesterol with a linear response up to 135 mu M. Furthermore, it has been observed that the biosensor exhibits a good anti-interference ability and favorable stability over a month's period.

• 出版日期2011-6-1