A New Pair of Pentaketide Diastereoisomers from Aspergillus melleus YIM PHI001

作者：Wang, Qiang; Yang, Xue-Qiong; Miao, Cui-Ping; Xu, Li-Hua; Ding, Zhong-Tao; Yang, Ya-Bin^*; Zhao, Li-Xing^*

来源：Records of Natural Products, 2018, 12(3): 216-221.

DOI：10.25135/rnp.12.17.04.065

• Aspergillus melleus
• aspinotriol derivatives
• diastereoisomer
• spectroscopic analyses
• antibiotic

Two new aspinotriol derivatives (1-2) determined as melleusin A (1), B (2) and other seven known compounds were isolated from a soil-borne fungus Aspergillus melleus. The configurations of 1, and 2 were determined by their analogues, aspilactonol B, C isolated previous in Aspergillus. Mellein (8) showed broad antibiotic activity against the test pathogens. Aspinonene, aspinotriols A and B can be used as the marker molecule in chemotaxonomy of Aspergillus.

• 出版日期2018-6
• 单位云南大学