A Chronic Subdural Hematoma in a Patient Receiving Combination Therapy with Pegylated Interferon Alfa-2b and Ribavirin for Chronic Hepatitis C

作者：Goto Takashi^*; Ohshima Shigetoshi; Miura Kouichi; Shibuya Tomomi; Sato Wataru; Dohmen Takahiro; Kamada Kentaro; Kanata Ryo; Sakai Toshitaka; Chiba Mitsuru; Sugimoto Yuko; Minami Shinichiro; Ohnishi Hirohide

来源：Internal Medicine, 2013, 52(18): 2057-2060.

DOI：10.2169/internalmedicine.52.0791

• pegylated interferon
• ribavirin
• chronic subdural hematoma

A 70-year-old man who suffered from chronic hepatitis C was infected with HCV genotype 1 and exhibited a high viral load. He had hypertension and had consumed the equivalent of 50 g of ethanol per day. He was treated with pegylated interferon and ribavirin. After 51 weeks, he developed an unsteady gait while walking and demonstrated Barre's sign on the right foot and a headache. Contrast computed tomography showed a subdural hematoma with a mass effect. The patient was treated with drainage and aspiration surgery via a burr hole. Following the drainage procedure, there were no neurological sequelae. Treatment with pegylated interferon and ribavirin was discontinued. Fortunately, a sustained virological response was achieved.

• 出版日期2013