An Approach for the Selective Detection of Nitric Oxide in Biological Systems: An invitro and invivo Perspective

作者：Gupta Neha; Reja Shahi Imam; Bhalla Vandana; Gupta Muskan; Kaur Gurcharan; Kumar Manoj^*

来源：Chemistry-An Asian Journal, 2016, 11(7): 1020-1027.

DOI：10.1002/asia.201501333

• biological activity
• imaging agents
• fluorescent probes
• lysosomes
• nitric oxide

A naphthalimide-based fluorescent probe, LyNP-NO, was designed and synthesized for the selective detection of exogenously and endogenously generated nitric oxide (NO) in C6 glial cells. In addition, LyNP-NO was also explored for monitoring endogenous NO levels in rat hippocampus at various tissue depths by stimulating the brain with N-methyl-d-aspartate (NMDA).

• 出版日期2016-4-5