ATG5 is required to limit cell death induced by Pseudomonas syringae in Arabidopsis and may be mediated by the salicylic acid pathway

作者：Wang, Jingchun; Ma, Chao; Zhang, Min; Yang, Liu; Chen, Wenli^*

来源：Acta Physiologiae Plantarum, 2015, 37(1): 1731.

DOI：10.1007/s11738-014-1731-5

• Arabidopsis
• Autophagy related 5
• Programmed cell death
• Pseudomonas syringae
• Salicylic acid signaling

Autophagy can be regarded as a protection mechanism to restrict programmed cell death (PCD) induced by pathogen infection during plant innate immunity in the early stages. Autophagy related 5 (ATG5) plays an important role in autophagy in Arabidopsis. We investigated the function of ATG5 in Arabidopsis in the hypersensitive response (HR)-PCD elicited by both virulent and avirulent strains of Pseudomonas syringae pv. tomato bacteria DC3000. Results show that ATG5 plays a vital role in limiting HR induced by P. syringae strains and colocalizes with autophagic bodies during the early phase of bacterial infection. In addition, the P. syringae-induced response is mediated by the salicylic acid (SA) signaling pathway. In summary, ATG5 is required for limiting HR-PCD induced in Arabidopsis by P. syringae strains and may be mediated by SA signaling.

• 出版日期2015-1
• 单位华南师范大学