Direct access to isoindolines through tandem Rh(III)-catalyzed alkenylation and cyclization of N-benzyltriflamides

作者：Mishra Neeraj Kumar; Park Jihye; Sharma Satyasheel; Han Sangil; Kim Mirim; Shin Youngmi; Jang Jinbong; Kwak Jong Hwan; Jung Young Hoon; Kim In Su^*

来源：Chemical communications, 2014, 50(18): 2350-2352.

DOI：10.1039/c3cc49486a

The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.

• 出版日期2014