Atrial aspiration from pulmonary and caval veins is caused by ventricular contraction and secures 70% of the total stroke volume independent of resting heart rate and heart size

作者：Steding Ehrenborg K; Carlsson M; Stephensen S; Arheden H^*

来源：Clinical Physiology and Functional Imaging, 2013, 33(3): 233-240.

DOI：10.1111/cpf.12020

• athletes
• cardiac magnetic resonance imaging
• cardiac pumping
• cardiac volume
• physiology

Background Whereas ventricular filling has been extensively studied and debated, atrial filling is less well characterized. Therefore, the aim of this study was to quantify atrial filling secured during ventricular diastole and systole, and to investigate whether atrial filling depends on heart rate (HR) and total heart volume (THV). Methods Thirty-two athletes (16 women) and 32 normal subjects (16 women) underwent cardiac magnetic resonance imaging. Cardiac volumes and atrioventricular plane displacement (AVPD) were determined. Longitudinal and radial contribution to stroke volume was calculated using planimetry and used to determine diastolic and systolic atrial filling. Results Atrial filling during ventricular diastole was 29 +/- 10% of the total stroke volume, and during ventricular systole atrial filling was 68 +/- 8% of the total stroke volume. There were no differences between groups of different HR (P=0 center dot 70 and P=0 center dot 41 for diastolic and systolic filling, respectively) or THV (P=0 center dot 44 and P=0 center dot 46 for diastolic and systolic filling, respectively). Systolic atrial filling was strongly correlated to longitudinal ventricular pumping (R=0 center dot 76, P<0 center dot 001). Conclusion This study demonstrated that in healthy humans at rest, approximately 30% of the total stroke volume enters the atria during ventricular diastole and approximately 70% during systole, independent of heart rate (HR) or heart size. The atria are filled through suction driven by ventricular longitudinal contraction which aspirates blood from the pulmonary and caval veins. As 70% of the atrial filling occurs during ventricular emptying, the heart volume remains relatively constant over the cardiac cycle, which minimizes pulling on surrounding tissues and therefore optimizes energy expenditure.

• 出版日期2013-5