Dermatomyositis associated with generalized subcutaneous edema and Evans syndrome

作者：Jung Kyu Dong; Kim Pyoung Su; Park Hae Young; Kim Cho Rok; Byun Ji Yeon; Lee Dong Youn; Lee Joo Heung; Yang Jun Mo^*; Lee Eil Soo

来源：Journal of the American Academy of Dermatology, 2012, 66(1): 144-147.

DOI：10.1016/j.jaad.2009.10.035

• dermatomyositis
• Evans syndrome
• generalized edema

Although periorbital edema is a common manifestation of dermatomyositis (DM), generalized subcutaneous edema associated with DM is extremely rare. Evans syndrome is an autoimmune disease in which an individual%26apos;s antibodies attack one%26apos;s own red blood cells and platelets. Evans syndrome is rarely a presenting feature of DM. DM has been rarely reported to be associated with either generalized edema or Evans syndrome. We report the case of a 52-year-old Korean woman who presented with generalized subcutaneous edema, an erythematous rash, dysphagia, and proximal muscle weakness, and subsequently developed features of Evans syndrome. Treatment with high-dose glucocorticoids and an immunosuppressive agent controlled the DM, the generalized subcutaneous edema, and the Evans syndrome. (J Am Acad Dermatol 2012;66:144-7.)

• 出版日期2012-1