A new diimide derivative from the co-culture broth of two mangrove fungi (strain no. E33 and K38)

作者:Li, Chun-Yuan; Ding, Wei-Jia; Shao, Chang-Lun; She, Zhi-Gang*; Lin, Yong-Cheng
来源:Journal of Asian Natural Products Research, 2010, 12(9): 809-813.
DOI:10.1080/10286020.2010.497757

摘要

A new diimide derivative, named (2)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthesis. Primary bioassays showed that 1 had weak cytotoxic activity against Hep-2 and HepG2 cells.