Applanatines A-E from the culture broth of Ganoderma applanatum

作者:Fushimi Keiji; Horikawa Madoka; Suzuki Kaori; Sekiya Atsushi; Kanno Susumu; Shimura Susumu; Kawagishi Hirokazu*
来源:Tetrahedron, 2010, 66(48): 9332-9335.
DOI:10.1016/j.tet.2010.10.014

摘要

Five novel compounds, applanatines A-E (1-5), and a known one (6) were isolated from the culture broth of Ganoderma applanatum. Their structures including the relative configurations were determined by the interpretation of spectroscopic data. Compounds 3 and 4 suppressed the growth of Fusobacterium nucleatum, that is, a prominent member of the oral microflora implicated in periodontitis.

  • 出版日期2010-11-27