Dynamic Contact Angle Analysis of Silicone Hydrogel Contact Lenses

作者:Read Michael Leonard; Morgan Philip Bruce; Kelly Jeremiah Michael; Maldonado Codina Carole*
来源:Journal of Biomaterials Applications, 2011, 26(1): 85-99.
DOI:10.1177/0885328210363505

摘要

Contact angle measurements are used to infer the clinical wetting characteristics of contact lenses. Such characterization has become more commonplace since the introduction of silicone hydrogel contact lens materials, which have been associated with reduced in vivo wetting due to the inclusion of siloxane-containing components. Using consistent methodology and a single investigator, advancing and receding contact angles were measured for 11 commercially available silicone hydrogel contact lens types with a dynamic captive bubble technique employing customized, fully automated image analysis. Advancing contact angles were found to range between 20 degrees and 72 degrees with the lenses falling into six statistically discrete groupings. Receding contact angles fell within a narrower range, between 17 degrees and 22 degrees, with the lenses segregated into three groups. The relationship between these laboratory measurements and the clinical performance of the lenses requires further investigation.

  • 出版日期2011-7