Desymmetrization of cyclic olefins via asymmetric Heck reaction and hydroarylation

作者:Liu Sijia; Zhou Jianrong*
来源:Chemical communications, 2013, 49(100): 11758-11760.
DOI:10.1039/c3cc47551d

摘要

An asymmetric Heck reaction allows desymmetrization of substituted cyclic olefins in high dr and ee. A bisphosphine oxide is uniquely stereoselective for this purpose. Desymmetrization of bicyclic olefins via hydroarylation can also be realized in high ee.

  • 出版日期2013