An atmospheric pressure ionization source based on desorption electrospray ionization technology (DESI) for ion cyclotron resonance mass spectrometry

作者：Agapov A Yu^*; Levitsky L I; Dashtiev N Z; Gorshkov M V; Tarasova I A

来源：Journal of Analytical Chemistry, 2011, 66(14): 1376-1384.

DOI：10.1134/S1061934811140024

• mass spectrometry
• atmospheric pressure ionization sources
• desorption electrospray ionization

An atmospheric pressure ionization source based on desorption electrospray ionization technology for a bench-top hybrid FTICR mass spectrometer is described. The ion source was characterized using low-molecular-weight-weight pharmaceutical samples. The dependences of signal intensities on various experimental parameters (solvent composition, surface temperature, spray voltage, etc.) were studied. Based on the results obtained, plausible mechanisms of desorption electrospray ionization for the analytes under the study are discussed.

• 出版日期2011-12