A review of biotransformation and pharmacology of ginsenoside compound K

作者：Yang Xi Ding; Yang Yong Yu; Ouyang Dong Sheng; Yang Guo Ping^*

来源：Fitoterapia, 2015, 100: 208-220.

DOI：10.1016/j.fitote.2014.11.019

• Ginsenoside compound K
• Ginseng
• Biotransformation
• Pharmacological activities

As an intestinal bacterial metabolite of ginseng protopanaxadiol saponins, ginsenoside compound K (20-O-beta-o-glucopyranosyl-20(S)-protopanaxadiol, CK) is a major deglycosylated metabolite form of ginsenosides which is absorbed into the systemic circulation. And it has demonstrated such diverse intriguing biological properties as anticarcinogenic, anti-inflammation, antiallergic, anti-diabetic, anti-angiogenesis, anti-aging, neuroprotective and hepatoprotective effects. The present review shall summarize recent studies on various biotransformation and pharmacological activities of CIC.

• 出版日期2015-1
• 单位中南大学