Ultrasonic histogram assessment of early response to concurrent chemoradiotherapy in patients with locally advanced cervical cancer: a feasibility study

作者：Xu, Yan; Ru, Tong; Zhu, Lijing; Liu, Baorui; Wang, Huanhuan; Zhu, Li; He, Jian; Liu, Song; Zhou, Zhengyang^*; Yang, Xiaofeng^*

来源：Clinical Imaging, 2018, 49: 144-149.

DOI：10.1016/j.clinimag.2018.01.002

• Ultrasonic histogram
• Cervical cancer
• Concurrent chemo-radiotherapy
• Therapy response

Purpose: To monitor early response for locally advanced cervical cancers undergoing concurrent chemo-radiotherapy (CCRT) by ultrasonic histogram. @@@ Methods: B-mode ultrasound examinations were performed at 4 time points in thirty-four patients during CCRT. Six ultrasonic histogram parameters were used to assess the echogenicity, homogeneity and heterogeneity of tumors. @@@ Results: I-peak increased rapidly since the first week after therapy initiation, whereas W-Iow, W-high and A(high) changed significantly at the second week. The average ultrasonic histogram progressively moved toward the right and converted into more symmetrical shape. @@@ Conclusion: Ultrasonic histogram could be served as a potential marker to monitor early response during CCRT.

• 出版日期2018-5
• 单位南京大学