Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the 'click' labelling of biomolecules

作者：Patra Malay; Metzler Nolte Nils^*

来源：Chemical Communications, 2011, 47(41): 11444-11446.

DOI：10.1039/c1cc14537a

A convenient synthesis of azidomethyl-ruthenocene and its use in the covalent labelling of amino acids, peptides and a peptide nucleic acid (PNA) monomer derivative by Cu(I) catalyzed azide-alkyne coupling (Cu-AAC, "click chemistry") are described.

• 出版日期2011