Direct copper(II)-mediated regioselective α-halogenation of N-aryl enaminones

作者：Xu, Hui; Zhou, Pan; Hang, Rong; Zhou, Jie; Lu, Ling-Ling; Shen, Yuehai^*; Yu, Fu-Chao^*

来源：Tetrahedron Letters, 2016, 57(45): 4965-4968.

DOI：10.1016/j.tetlet.2016.09.076

• Halogenation
• N-Aryl enaminones
• alpha-Halogenated N-aryl enaminones
• Regioselective
• Copper(II) halide

A mild copper(II)-mediated alpha-halogenation of N-aryl enaminones was developed. alpha-Halogenated N-aryl enaminones were obtained in moderate to good yields using CuX2 in EtOH at 40 degrees C.

• 出版日期2016-11-9
• 单位云南大学; 昆明理工大学