Burden of disease due to cutaneous melanoma has increased in the Netherlands since 1991

作者：Holterhues C; Hollestein L M^*; Nijsten T; Koomen E R; Nusselder W; de Vries E

来源：British Journal of Dermatology, 2013, 169(2): 389-397.

DOI：10.1111/bjd.12346

Background The burden of disease, describing loss of health and death due to a disease, has not been fully studied for melanoma in the general population over time. %26lt;br%26gt;Objectives To determine the burden of disease due to melanoma in the Netherlands. %26lt;br%26gt;Methods Age- and sex-specific incidence data from all patients with melanoma in the Netherlands between 1991 and 2010 were obtained from the Netherlands Cancer Registry. Melanoma-specific mortality and life expectancy data were obtained from Statistics Netherlands. Melanoma duration was calculated using the DISMOD software from the World Health Organization. The years of life lived with disability (YLD) and years of life lost (YLL) due to melanoma were calculated using Dutch disability weights, incidence and mortality of melanoma, and the life expectancy from the general population. The number of disability-adjusted life-years (DALYs) was estimated by adding YLD and YLL. %26lt;br%26gt;Results The world-standardized incidence rates of melanoma have more than doubled for both men (71 per 100000 inhabitants in 1991 to 170 in 2010) and women (94 per 100000 inhabitants in 1991 to 198 in 2010). Likewise, the burden of melanoma to society has increased rapidly. The YLD for men increased from 4795 (1991-4) to 12441 (2007-10), and for women from 7513 (1991-4) to 16544 (2007-10). In 2007-10 the total YLL due to melanoma was 30651 for men and 26244 for women compared with 17238 and 16900, respectively, in 1991-4. The DALYs increased by 96% for men, from 22033 (1991-4) to 43092 (2007-10), and by 75% for women, from 24413 (1991-4) to 42788 (2007-10). %26lt;br%26gt;Conclusions Melanoma is becoming a great burden to Dutch society.

• 出版日期2013-8