A new tropane alkaloid and other constituents of Erythroxylum rimosum (Erythroxylaceae)

作者：Ribeiro Erika M de O; Lima Luciano S; David Jorge M; do Vale Ademir E; Lopes Lucia M X; David Juceni P^*

来源：Phytochemistry Letters, 2013, 6(2): 232-235.

DOI：10.1016/j.phytol.2013.02.008

• Erythroxylum rimosum
• Erythroxylaceae
• Tropane alkaloid
• Flavonoids
• Triterpenes
• Acetylcholinesterase inhibition

A new tropane alkaloid, named the 7 beta-acetoxy-3 beta,6 beta-dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-alpha-L-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-alpha-arabinofuranoside, quercetin-3-O-alpha-arabinopyranoside, quercetin-3-O-beta-arabinopyranoside, quercetin-3-beta-glucopyranoside, kaempferol, quercetin-3-O-beta-galactopyranoside, beta-sitosterol, alpha-amyrin, beta-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data.

• 出版日期2013-5